Anti-GBM-associated crescentic glomerulonephritis with discrete IgG deposition, but with no electron-dense material in glomeruli.

Crescentic glomerulonephritis is characterized by extracapillary proliferation resulting from severe inflammatory injury of various aetiologies. It is usually rapidly progressive. Meanwhile, anti-glomerular basement membrane (GBM) antibody-mediated glomerular lesions induce crescentic glomerulonephritis. When associated with pulmonary haemorrhage, it is given the eponym 'Goodpasture's syndrome'. However, anti-GBM glomerulonephritis without evidence of pulmonary purpura occurs in about 30% of patients with crescentic glomerulonephritis [1]. On the other hand, anti-GBM glomerulonephritis is also characterized by linear deposition of IgG in the GBM. Some patients with anti-GBM glomerulonephritis exhibit granular or non-linear IgG deposits indicating the involvement of an immune complexmediated event [2]. We present a case of anti-GBM glomerulonephritis with non-linear IgG deposits in the glomerular capillary wall without evidence of subepithelial or subendothelial deposits of immune complexes.